/* VialDose — shared styles. Static, zero dependencies. v3 */
:root {
  --green: #0e7a4f;
  --green-dark: #0a5c3c;
  --green-soft: #e7f4ee;
  --green-mist: #f2faf6;
  --ink: #16201b;
  --muted: #5c6660;
  --hairline: #e4e8e5;
  --bg: #ffffff;
  --bg-soft: #f6f8f7;
  --danger: #b3261e;
  --danger-soft: #fdecea;
  --radius: 12px;
  --shadow-sm: 0 1px 2px rgba(20, 40, 30, 0.05), 0 1px 6px rgba(20, 40, 30, 0.04);
  --shadow-md: 0 2px 6px rgba(20, 40, 30, 0.06), 0 14px 36px rgba(16, 64, 42, 0.11);
  --shadow-lg: 0 4px 10px rgba(16, 64, 42, 0.07), 0 24px 60px rgba(16, 64, 42, 0.13);
}
* { box-sizing: border-box; }
html { -webkit-text-size-adjust: 100%; }
body {
  margin: 0;
  font-family: -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, Helvetica, Arial, sans-serif;
  color: var(--ink);
  line-height: 1.65;
  font-size: 16px;
  background:
    radial-gradient(560px 260px at 12% -40px, rgba(46, 163, 111, 0.20), transparent 70%),
    radial-gradient(640px 300px at 88% -60px, rgba(14, 122, 79, 0.14), transparent 70%),
    linear-gradient(180deg, #e2f1e9 0%, #f0f9f4 55%, var(--bg) 100%) no-repeat top / 100% 560px,
    var(--bg);
}
body::before {
  content: ""; display: block; height: 4px;
  background: linear-gradient(90deg, var(--green-dark), var(--green) 40%, #2ea36f 70%, var(--green-dark));
}
::selection { background: rgba(14, 122, 79, 0.20); }
.wrap { max-width: 760px; margin: 0 auto; padding: 0 20px; }

/* ---------- tool pages: calculator becomes the hero ---------- */
main.wrap:has(.calc) { max-width: 1020px; }
main.wrap:has(.calc) > h1,
main.wrap:has(.calc) > .lead,
main.wrap:has(.calc) > h2,
main.wrap:has(.calc) > p,
main.wrap:has(.calc) > ul,
main.wrap:has(.calc) > .faq,
main.wrap:has(.calc) > .disclaimer {
  max-width: 780px; margin-left: auto; margin-right: auto;
}
main.wrap:has(.calc) > h1 { text-align: center; }
main.wrap:has(.calc) > .lead { text-align: center; }
main.wrap:has(.calc) > .calc,
main.wrap:has(.calc) > .grid-links,
main.wrap:has(.calc) > .cta { max-width: 900px; margin-left: auto; margin-right: auto; }

header.site {
  background: rgba(255, 255, 255, 0.86);
  backdrop-filter: saturate(1.4) blur(10px);
  -webkit-backdrop-filter: saturate(1.4) blur(10px);
  border-bottom: 1px solid var(--hairline);
  position: sticky; top: 0; z-index: 10;
}
header.site .wrap { display: flex; align-items: center; justify-content: space-between; height: 60px; }
.brand {
  font-weight: 800; font-size: 19px; color: var(--ink); text-decoration: none; letter-spacing: -0.02em;
  display: inline-flex; align-items: center; gap: 0; /* brand name must render as one word: VialDose (gap only via logo margin) */
}
.brand-logo {
  width: 26px; height: 26px; border-radius: 7px; flex: none; margin-right: 9px;
  box-shadow: 0 2px 5px rgba(10, 60, 40, 0.30);
}
.brand span { color: var(--green); }
nav.top { display: flex; align-items: center; }
nav.top a { color: var(--muted); text-decoration: none; font-size: 14.5px; margin-left: 20px; font-weight: 550; }
nav.top a:hover { color: var(--green); }

main { padding: 44px 0 8px; }
h1 {
  font-size: clamp(30px, 5.2vw, 44px); line-height: 1.14; margin: 0 0 14px;
  letter-spacing: -0.03em; font-weight: 850;
}
h2 { font-size: 23px; margin: 44px 0 14px; letter-spacing: -0.015em; font-weight: 780; display: flex; align-items: center; gap: 11px; }
h2::before { content: ""; width: 5px; height: 21px; border-radius: 3px; background: var(--green); flex: none; }
h3 { font-size: 17.5px; margin: 24px 0 8px; }
p, li { color: #2c332f; }
.lead { font-size: 18.5px; color: #46524b; margin: 0 0 30px; max-width: 680px; }
a { color: var(--green); }

/* "works with" compound strip under the lead on index */
.works-with { text-align: center; font-size: 15px; color: var(--muted); margin: -22px 0 30px; }
.works-with a { color: var(--green); font-weight: 700; text-decoration: none; border-bottom: 1px solid var(--green-mist); }
.works-with a:hover { border-bottom-color: var(--green); }

/* ---------- footer: dark green finish ---------- */
footer.site { margin-top: 64px; background: linear-gradient(180deg, #0e4630, #0a3524); color: #cfe8da; }
footer.site .wrap { padding: 34px 20px 42px; font-size: 13.5px; color: #a8d3bc; }
footer.site a { color: #a8d3bc; margin-right: 18px; text-decoration: none; }
footer.site a:hover { color: #ffffff; text-decoration: underline; }

.card {
  border: 1px solid var(--hairline); border-radius: var(--radius);
  background: var(--bg); padding: 20px; margin: 18px 0; box-shadow: var(--shadow-sm);
}
.card.soft { background: var(--bg-soft); border-color: transparent; }

.cta {
  border: 1px solid #c3e4d2; border-radius: 16px;
  background: linear-gradient(135deg, var(--green-soft), #eefaf4 60%, #ffffff);
  box-shadow: var(--shadow-sm);
  padding: 24px 26px; margin: 40px 0 30px;
  display: flex; gap: 16px; align-items: center; justify-content: space-between; flex-wrap: wrap;
}
.cta .small { font-size: 13.5px; }

.btn {
  display: inline-block; color: #fff; text-decoration: none;
  padding: 12px 22px; border-radius: 11px; font-weight: 700; font-size: 15.5px; border: 0; cursor: pointer;
  background: linear-gradient(180deg, #14895b, var(--green) 55%, var(--green-dark));
  box-shadow: 0 2px 4px rgba(10, 60, 40, 0.28), inset 0 1px 0 rgba(255, 255, 255, 0.20);
  transition: transform 0.08s ease, box-shadow 0.12s ease;
}
.btn:hover { background: linear-gradient(180deg, #108a5c, var(--green-dark) 55%, #084c32); box-shadow: 0 4px 12px rgba(10, 60, 40, 0.30), inset 0 1px 0 rgba(255, 255, 255, 0.20); }
.btn:active { transform: translateY(1px); }
.btn.ghost { background: var(--bg); color: var(--green); border: 1px solid #bcd9c9; box-shadow: none; }
.btn.ghost:hover { background: var(--green-mist); border-color: var(--green); }

/* ---------- calculator ---------- */
.calc {
  position: relative;
  border: 1px solid #d6e3db; border-radius: 20px; padding: 28px 28px 22px; background: var(--bg);
  box-shadow: var(--shadow-lg);
}
.calc::after {
  content: "100% FREE";
  position: absolute; top: -14px; right: 24px;
  background: linear-gradient(135deg, #18a56b, var(--green) 60%, var(--green-dark));
  color: #fff; font-size: 11.5px; font-weight: 800; letter-spacing: 0.08em;
  padding: 5px 13px; border-radius: 999px;
  box-shadow: 0 3px 8px rgba(10, 60, 40, 0.30), inset 0 1px 0 rgba(255, 255, 255, 0.25);
}
.calc h2 { margin-top: 0; }
.calc .row { display: grid; grid-template-columns: 1fr 1fr; gap: 14px 18px; }
.calc .row3 { display: grid; grid-template-columns: 1fr 1fr 1fr; gap: 14px; }
@media (max-width: 560px) { .calc .row, .calc .row3 { grid-template-columns: 1fr; } }
.calc label {
  display: block; font-size: 12.5px; font-weight: 750; color: var(--muted);
  margin: 14px 0 5px; text-transform: uppercase; letter-spacing: 0.05em;
}
.calc input, .calc select {
  width: 100%; padding: 12px 14px; font-size: 16px;
  border: 1px solid #d3ded7; border-radius: 10px; background: var(--bg); color: var(--ink);
  transition: border-color 0.12s ease, box-shadow 0.12s ease;
}
.calc input:hover, .calc select:hover { border-color: #b4cabd; }
.calc input:focus, .calc select:focus {
  outline: none; border-color: var(--green);
  box-shadow: 0 0 0 3px rgba(14, 122, 79, 0.15);
}
.calc .foot {
  font-size: 12.5px; color: var(--muted); border-top: 1px solid var(--hairline);
  margin-top: 22px; padding-top: 14px; text-align: center;
}

.result { margin-top: 20px; border-radius: 14px; overflow: hidden; }
.result .ok { background: linear-gradient(135deg, #e0f3e8, var(--green-soft)); border: 1px solid #c5e4d3; padding: 18px 20px; }
.result .err { background: var(--danger-soft); border: 1px solid #f3c7c3; padding: 16px 18px; color: var(--danger); font-weight: 600; }
.result .warn { background: #fdf3d7; border: 1px solid #ecd28a; padding: 18px 20px; }
.result .warn .big { color: #8a6d1a; }
.result .small-warn { font-size: 13px; color: #8a6d1a; margin-top: 8px; border-top: 1px dashed #e0c46a; padding-top: 8px; }
.result .note { font-size: 12.5px; color: #365c8a; margin-top: 8px; border-top: 1px dashed #bcd0e4; padding-top: 8px; }
.result .placeholder {
  border: 1.5px dashed #cdd9d1; border-radius: 12px; padding: 22px 16px;
  text-align: center; color: var(--muted); font-size: 14px; background: var(--bg-soft);
}
.result .big { font-size: 27px; font-weight: 800; letter-spacing: -0.02em; margin: 2px 0; color: var(--green-dark); }
.result .sub { font-size: 14px; color: var(--muted); }
.result .exact { font-size: 12px; color: var(--muted); margin-top: 6px; font-variant-numeric: tabular-nums; }
svg.syr { width: 100%; height: auto; display: block; margin-top: 12px; }
.copyline .copied { font-size: 13px; color: var(--green); font-weight: 700; }

/* ---------- half / double quick buttons ---------- */
.calc .quick { display: flex; align-items: center; gap: 7px; margin-top: 8px; flex-wrap: wrap; }
.calc .quick > span { font-size: 11.5px; color: var(--muted); font-weight: 600; letter-spacing: 0.02em; }
.chip {
  font: inherit; font-size: 12.5px; font-weight: 750; line-height: 1;
  padding: 6px 11px; border-radius: 999px; cursor: pointer;
  color: var(--green-dark); background: var(--green-mist);
  border: 1px solid #c9e3d6;
  transition: background 0.12s ease, border-color 0.12s ease, transform 0.08s ease;
}
.chip:hover { background: var(--green-soft); border-color: var(--green); }
.chip:active { transform: translateY(1px); }
.chip:focus-visible { outline: none; box-shadow: 0 0 0 3px rgba(14, 122, 79, 0.18); }

/* ---------- dose ladder (titration table) ---------- */
.ladder { margin-top: 18px; }
.ladder:empty { display: none; }
.ladder-head {
  display: flex; align-items: baseline; justify-content: space-between; gap: 10px; flex-wrap: wrap;
  border-top: 1px solid var(--hairline); padding-top: 16px; margin-bottom: 10px;
}
.ladder-head h4 { margin: 0; font-size: 14px; font-weight: 800; letter-spacing: -0.01em; color: var(--ink); }
.ladder-head .hint { font-size: 11.5px; color: var(--muted); }
.ladder table.t { margin: 0; font-size: 13.5px; }
.ladder th { font-size: 12px; text-transform: uppercase; letter-spacing: 0.04em; color: var(--muted); }
.ladder td, .ladder th { padding: 8px 10px; }
.ladder tr[data-step]:not([data-step="1"]) { cursor: pointer; transition: background 0.1s ease; }
.ladder tr[data-step]:not([data-step="1"]):hover { background: var(--green-mist); }
.ladder tr[data-step]:focus-visible { outline: 2px solid var(--green); outline-offset: -2px; }
.ladder tr.current td { background: var(--green-soft); }
.ladder tr.current td:first-child { box-shadow: inset 3px 0 0 var(--green); }
.ladder tr.over td { color: #94a09a; }
.ladder tr.over td:nth-child(3)::after { content: " › cap"; font-size: 10.5px; letter-spacing: 0.02em; }
.ladder .tag {
  display: inline-block; font-size: 10px; font-weight: 800; letter-spacing: 0.06em;
  text-transform: uppercase; color: #fff; background: var(--green);
  padding: 2px 6px; border-radius: 999px; vertical-align: 1px;
}
.ladder .ladder-foot { font-size: 11.5px; color: var(--muted); margin-top: 8px; line-height: 1.5; }
/* v3: schedule column appears only for per-molecule reference escalations */
.ladder td.sched { white-space: nowrap; color: var(--muted); font-size: 12.5px; }
.ladder tr.over td.sched { color: #aab4ae; }
@media (max-width: 560px) {
  .ladder table.t { font-size: 12.5px; }
  .ladder td, .ladder th { padding: 7px 7px; }
  /* five columns (dose / schedule / mL / units / per vial) gets tight — shrink the
     least important column first rather than letting the row wrap */
  .ladder td.sched { font-size: 11px; letter-spacing: -0.01em; }
}

/* ---------- content helpers ---------- */
.faq { background: var(--bg); border: 1px solid var(--hairline); border-radius: 14px; padding: 10px 26px 6px; box-shadow: var(--shadow-sm); }
.faq dt { font-weight: 750; margin-top: 0; padding-top: 14px; border-top: 1px solid var(--hairline); }
.faq dt:first-child { border-top: 0; padding-top: 8px; }
.faq dd { margin: 4px 0 14px; padding-bottom: 14px; border-bottom: 1px solid var(--hairline); color: #2c332f; }
.faq dd:last-of-type { border-bottom: 0; }

table.t { width: 100%; border-collapse: collapse; margin: 14px 0; font-size: 14.5px; border-radius: 10px; overflow: hidden; box-shadow: var(--shadow-sm); }
table.t th, table.t td { border: 1px solid var(--hairline); padding: 9px 12px; text-align: left; }
table.t th { background: var(--green-mist); color: var(--ink); font-weight: 750; }
table.t td.num { font-variant-numeric: tabular-nums; }
/* v3: static reference escalation table (per-molecule published schedule) */
main.wrap > table.ref-table { margin-bottom: 18px; }
table.ref-table td:first-child { white-space: nowrap; }
/* source attribution line under a reference table */
p.src { font-size: 12.5px; color: var(--muted); margin: -6px 0 32px; line-height: 1.6; }
table.ref-table + p.disclaimer { margin-top: 18px; }
.small { font-size: 13px; color: var(--muted); }
.disclaimer {
  background: var(--bg-soft); border: 1px solid var(--hairline); border-left: 4px solid #b8c4bd;
  border-radius: 10px; padding: 14px 16px; font-size: 13.5px; color: var(--muted); margin: 30px 0;
}
ul.checks { padding-left: 20px; }
ul.checks li { margin: 7px 0; }
ul.checks li::marker { color: var(--green); }

.breadcrumb { font-size: 13px; color: var(--muted); margin-bottom: 14px; }
.breadcrumb a { color: var(--muted); }

.grid-links { display: grid; grid-template-columns: repeat(auto-fit, minmax(250px, 1fr)); gap: 14px; margin: 20px 0; }
.grid-links a {
  display: block; border: 1px solid #dbe6df; border-radius: 13px; padding: 15px 17px;
  text-decoration: none; color: var(--ink); font-weight: 700; font-size: 14.5px;
  background: var(--bg); box-shadow: var(--shadow-sm);
  transition: transform 0.1s ease, box-shadow 0.12s ease, border-color 0.12s ease;
}
.grid-links a::before { content: "→ "; color: var(--green); font-weight: 800; }
.grid-links a:hover {
  border-color: var(--green); transform: translateY(-2px);
  box-shadow: 0 4px 10px rgba(20, 40, 30, 0.08), 0 12px 28px rgba(14, 122, 79, 0.12);
}
.grid-links a span { display: block; font-weight: 450; font-size: 13px; color: var(--muted); margin-top: 3px; }

/* formula pills on index "How the math works" */
.formula {
  display: inline-block; background: var(--green-mist); border: 1px solid #cfe4d8;
  border-radius: 10px; padding: 11px 17px; margin: 6px 6px 6px 0;
  font-family: ui-monospace, "Cascadia Mono", Consolas, monospace; font-size: 14.5px; color: var(--green-dark);
  max-width: 100%; white-space: normal; word-break: break-word;
}

/* small screens */
@media (max-width: 560px) {
  header.site .wrap { height: 52px; }
  .brand { font-size: 17px; }
  nav.top a { margin-left: 12px; font-size: 13px; }
  .calc { padding: 20px 16px 16px; border-radius: 16px; }
  .calc::after { right: 14px; }
}